New research suggests that repeated mRNA vaccination induces limited immune tolerance for the spike protein
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“Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination” is the title of a new Science: Immunology paper by researchers at Erlangen, in Germany.
It’s already been covered by friends-of-the blog:
We desperately need to transition to a world where we stop worrying about virus infections, particularly infections with Corona.
It looks like repeated mRNA vaccination induces a partial immune tolerance of the spike protein. Adenovirus vector vaccines don’t cause this tolerance. The spike protein on its own doesn’t either. Nor do vaccines against other pathogens cause this kind of tolerance for their respective antigens. Everything suggests it’s a property of the mRNA technology in particular.
See the other post on the topic: